Sean Smith, PhD

I started Smith BioAdvisory to help biotech teams move great science from possibility to plans and data. I’m an immuno‑engineer by training with deep experience in immunology, cytokine‑armored cell therapies (IL‑12/IL‑15), and drug delivery (liposomes, hydrogels, intratumoral, intravesical). I love bridging disciplines and teams to enable clear communication and decision making.

I’ll meet you where you are—then help you get where you’re going with clarity, alignment, and less risk.

Services & Focus Areas

  • Preclinical drug development

    • Experimental design and hands-on execution

    • Lead candidate definition and selection

    • CRO management

  • Due diligence & scientific rationale assessments (target, modality, mechanism, translational fit)

    • Cell therapy & immunology (cytokine‑armored T cells, TIL, innate/adaptive interfaces)

    • Nanoparticle/drug‑delivery strategy (liposomes, LNPs, depot concepts)

    • Disease specific expertise and preclinical modeling (Bladder cancer, ovarian cancer, autoimmunity)

  • KOL selection and outreach for advisory boards

  • Non‑dilutive funding strategy & execution (NIH/DoD/foundations; scope, authoring, and submission)

  • Scientific storytelling (partner/investor decks, grants, data packages)

Contact us

Interested in working together? Fill out some info and we will be in touch shortly. We can’t wait to hear from you!